Olepra Tablets Specifications
- Prescription Required: Yes
- Generics: Olanzapine
- Used For: Schizophrenia, moderate to severe manic episodes
Mechanism of Action Olanzapine is an atypical (second-generation) antipsychotic that primarily affects dopamine and serotonin receptors. It acts as an antagonist at dopamine D2 receptors in the mesolimbic pathway, blocking dopamine from acting at the post-synaptic receptor.
Olepra Tablets Usage and Safety
- Dosage: Olanzapine
- Side Effects:
- Common (may affect up to 1 in 10 people): Unusual movements mainly of the face or tongue.
- Uncommon (may affect up to 1 in 100 people): Blood clots in the veins, especially in the legs (symptoms include swelling, pain, and redness), which may travel to the lungs causing chest pain and difficulty in breathing. Seek medical advice immediately if you notice any of these symptoms.
- Rare: A combination of fever, faster breathing, sweating, muscle stiffness, and drowsiness or sleepiness.
- Drug Interactions:
- Hepatotoxic drugs
- CNS active drugs
- Alcohol
- Drugs that increase QTc interval
- Charcoal
- Smoking
- CYP1A2 inducers or inhibitors (e.g., carbamazepine, fluvoxamine, ciprofloxacin, nicotine)
- Benzodiazepines
- Other CNS depressants
- Dopaminergics
Indications Olepra Tablets are used to treat schizophrenia and moderate to severe manic episodes, conditions characterized by symptoms of excitement or euphoria.
Contraindications Do not take Olepra if you are allergic (hypersensitive) to olanzapine or any of the other ingredients in this medicine. An allergic reaction may be recognized as a rash, itching, swollen face, swollen lips, or shortness of breath. If this occurs, inform your doctor immediately.
Olepra Tablets Precautions The use of Olanzapine in elderly patients with dementia is not recommended due to potential serious side effects.
Olepra Tablets Warnings
- Movement Disorders: Medicines of this type may cause unusual movements, mainly of the face or tongue. Inform your doctor if this occurs.
- Serious Reaction: Rarely, medicines of this type cause a combination of fever, faster breathing, sweating, muscle stiffness, and drowsiness or sleepiness. Contact your doctor at once if this happens.
- Weight Gain: Weight gain has been observed in patients taking Olanzapine. Regular weight checks are recommended. Consider consulting a dietitian for a diet plan if necessary.
Additional Information
- Pregnancy Category: Always consult your physician before using any medicine.
- Storage: Store this medicine at room temperature, away from direct light and heat.
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