Risek Capsules

Risek Capsules Specification

Requires Prescription: Yes

Generic Name: Omeprazole

Used For: Gastroesophageal Reflux Disease (GERD)

How it Works: Omeprazole inhibits gastric acid secretion by blocking the H+/K+ ATPase enzyme system, also known as the proton pump, in the stomach lining. This action reduces both basal and stimulated acid production.

Risek Capsules Usage and Safety

Dosage: Omeprazole

Side Effects:

• Common: Headache, diarrhea, constipation, abdominal pain, nausea/vomiting, flatulence.
• Uncommon: Dizziness, paraesthesia, somnolence, insomnia, vertigo, increased liver enzymes, rash, pruritis, urticaria, malaise.
• Rare: Reversible mental confusion, agitation, aggression, depression, hallucinations (mainly in severely ill patients), gynecomastia.

Drug Interactions:

• Ketoconazole, itraconazole, diazepam, citalopram, imipramine, clomipramine, phenytoin, atazanavir, digoxin, clopidogrel, posaconazole, erlotinib, saquinavir, tacrolimus, methotrexate, clarithromycin, CYP2C19 or CYP3A4 inhibitors (e.g., rifampicin, St. John’s wort).

Indications:

• Treatment of erosive reflux esophagitis
• Long-term management of healed esophagitis to prevent relapse
• Symptomatic treatment of GERD

When Not to Use:

• Hypersensitivity to any component of the formulation or to substituted benzimidazoles.
• Concurrent use with nelfinavir.

Risek Capsules Precautions:

• Omeprazole may reduce vitamin B12 absorption. Consider this in patients with reduced body stores or risk factors for reduced B12 absorption on long-term therapy.

Risek Capsules Warnings:

1. Exclude the possibility of gastric malignancy if a gastric ulcer is suspected, as treatment may alleviate symptoms and delay diagnosis.
2. Long-term use of proton pump inhibitors, especially in high doses, may increase the risk of hip, wrist, and spine fractures, particularly in the elderly or those with other risk factors.
3. Consider dose reduction in patients with impaired hepatic function due to increased bioavailability and half-life.

Additional Information:

• Pregnancy Category: Always consult your physician before using any medicine.
• Storage: Store at room temperature, away from direct light and heat.