Deprel Tablets Specification
Requires Prescription: Yes
Generics: Trazodone HCl
Used For: Depression
How it works: Trazodone HCl inhibits serotonin uptake in brain synaptosomes and rat platelets at higher concentrations, and it also affects noradrenaline uptake in vitro. It exhibits antiserotonin-adrenergic blocking and analgesic effects. Compared to tricyclic antidepressants, trazodone shows less anticholinergic activity in animal studies and therapeutic trials with depressed patients confirm this.
Deprel Tablets Usage And Safety
Dosage: Trazodone HCl
Side Effects:
- Thoughts of self-harm or suicide
- Fatigue, dizziness, pale skin (signs of anemia)
- Seizures
- Abnormal skin sensations (paresthesia)
- Confusion, restlessness, hallucinations, muscle twitches (serotonin syndrome)
- Neuroleptic Malignant Syndrome symptoms like high fever and muscle rigidity
- Rapid, slow, or irregular heartbeat
Drug Interactions:
- MAOIs (Monoamine Oxidase Inhibitors)
- Muscle relaxants and inhaled anesthetics
- Other antidepressants and sedatives
- Medications for epilepsy, high blood pressure, heart disease
- Antifungal medications, HIV treatments, antibiotics, and others
Indication: Used for all types of depression, including those accompanied by anxiety.
When not to Use: Avoid if allergic to trazodone HCl or any ingredients, recently had a heart attack, are heavy drinker, taking sleeping tablets, or under 18 years old.
Deprel Tablets Precautions
Precaution: Stopping the medication abruptly may lead to sleep disturbances, irritability, and increased sweating.
Deprel Tablets Warnings
Warning 1: Elderly individuals are more susceptible to side effects; caution needed when taking other medications simultaneously or with existing conditions.
Warning 2: Initial use of antidepressants may increase thoughts of self-harm or suicide; effects may take up to two weeks to manifest.
Warning 3: Trazodone affects the central nervous system, causing drowsiness or reduced alertness. Avoid driving or operating machinery until effects are known.
Deprel Tablets Additional Information
Pregnancy category: Always consult a physician before use.
Storage: Store at room temperature, away from light and heat.
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