Qusel Tablets

Qusel Tablets Specifications:

• Prescription Required: Yes
• Generics: Quetiapine Fumarate
• Used For: Schizophrenia
• Mechanism of Action: Quetiapine’s exact mechanism is not fully understood. It is believed to work through dopamine D2 and serotonin 5HT2 antagonism. Its effects on histamine H1 and adrenergic a1 receptors may explain side effects like somnolence and orthostatic hypotension.

Qusel Tablets Usage and Safety:

• Dosage: Quetiapine Fumarate
• Common Side Effects: Somnolence, dizziness, dry mouth, constipation, dyspepsia, postural hypotension, elevated ALT (SGPT) levels, weight gain.
• Drug Interactions: Includes phenytoin, thioridazine, oxycodone, acetaminophen, barbiturates, sedatives (e.g., alprazolam, clonazepam), ethanol, prazosin, terazosin, ketoconazole, itraconazole, fluconazole, erythromycin, clarithromycin, nefazodone, verapamil, diltiazem.

Indication:

• Quetiapine is indicated for treating schizophrenia.

When Not to Use:

• Contraindicated in individuals hypersensitive to quetiapine or its components.

Precautions:

• Use in pediatric patients under 18 years is not established.

Warnings:

1. May cause neuroleptic malignant syndrome, tardive dyskinesia, hypotension, syncope, especially during initial dosing.
2. Regular eye examinations recommended; discontinue if significant changes occur.
3. Use cautiously in moderate to severe hepatic impairment, renal impairment, cardiovascular disease, temperature regulation issues, hyperglycemia.

Additional Information:

• Pregnancy Category: Consult physician before use.
• Storage: Store at room temperature, away from direct light and heat.