Zoloft Tablets (1 Box = 3 Strips) (1 Strip = 10 Tablets)

Zoloft Tablets Specification

Requires Prescription: Yes

Generics: Sertraline HCl

Used For: Depression

How it Works: Sertraline increases serotonergic activity in the central nervous system by inhibiting the reuptake of serotonin (5-HT).

Zoloft Tablets Usage and Safety

Dosage: Sertraline HCl

Side Effects:

• Hypersensitivity reactions
• Disulfiram-alcohol reaction when taken with disulfiram
• QT prolongation and ventricular arrhythmias when taken with pimozide
• Suicidal thoughts and behaviors
• Serotonin syndrome
• Increased risk of bleeding
• Activation of mania/hypomania
• Discontinuation syndrome
• Seizures
• Angle-closure glaucoma
• Hyponatremia

Drug Interactions:

• MAOIs (e.g., selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue)
• Other SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John’s Wort
• Aspirin, clopidogrel, heparin, warfarin
• Propafenone, flecainide, atomoxetine, desipramine, dextromethorphan, metoprolol, nebivolol, perphenazine, thoridazine, tolterodine, venlafaxine
• Fosphenytoin

Indication:

• Major depressive disorder (MDD)
• Obsessive-compulsive disorder (OCD)
• Panic disorder (PD)

When not to Use:

• Within 14 days of stopping MAOIs due to the risk of serotonin syndrome
• With pimozide
• Known hypersensitivity to sertraline (e.g., anaphylaxis, angioedema)

Zoloft Tablets Precautions

Precaution:

• Exposure to SSRIs and SNRIs in late pregnancy may lead to increased risks for neonatal complications, including prolonged hospitalization, respiratory support, and tube feeding, and/or persistent pulmonary hypertension of the newborn (PPHN).

Zoloft Tablets Warnings

Warning 1:

• SNRIs and SSRIs can precipitate serotonin syndrome, a potentially life-threatening condition.

Warning 2:

• Sertraline increases the risk of bleeding events. Concomitant use of aspirin, NSAIDs, other antiplatelet drugs, warfarin, and other anticoagulants may add to this risk.

Warning 3:

• Hyponatremia may occur as a result of treatment with SNRIs and SSRIs, including cases with serum sodium lower than 110 mmol/L.

Zoloft Tablets Additional Information

Pregnancy Category: Always consult your physician before using any medicine.

Storage: Store at room temperature, away from direct light and heat.